Can I Put more than 80 gig hard drive as a master hard drive is there a limit?

I have an AMD Athlon 1800 1.8 gighertz Motherboard and widows xp home at present the master hard drive is a 80 gig hard drive but want to get a 500 gig hard drive could i put that as my main master hard drive or wouldnt it work or are you restricted or limited with windows xp as to the capacity xp would take as a Master hard drive? your help would be greatly appreciated and thanks in anticipation of your help